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Public Health Genomics and Precision Health Knowledge Base (v9.0)
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Precision Health Database|Search|Public Health Genomics and Precision Health Knowledge Base (PHGKB)
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Last data update: May 16, 2024
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Management of Down Syndrome-Associated Leukemias: A Review.
Anupam Verma et al. JAMA Oncol 2023
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Impact of TP53 gene variants on prognosis and survival of childhood acute lymphoblastic leukemia.
Sinem Firtina et al. Scandinavian journal of clinical and laboratory investigation 2023 1-7
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IL16 and factor V gene variations are associated with asparaginase-related thrombosis in childhood acute lymphoblastic leukemia patients.
Covida Mootoosamy et al. Pharmacogenomics 2023
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Design and Validation of a Custom Next-Generation Sequencing Panel in Pediatric Acute Lymphoblastic Leukemia.
José Vicente Gil et al. International journal of molecular sciences 2023 24(5)
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Diagnostic utility of whole genome sequencing in adults with B-other acute lymphoblastic leukemia.
Daniel Leongamornlert et al. Blood advances 2023
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Pharmacotypes across the genomic landscape of pediatric acute lymphoblastic leukemia and impact on treatment response.
Lee Shawn H R et al. Nature medicine 2023
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Association of Inherited Genetic Factors With Drug-Induced Hepatic Damage Among Children With Acute Lymphoblastic Leukemia.
Yang Wenjian et al. JAMA network open 2022 5(12) e2248803
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Deep learning-based transcriptome model predicts survival of T-cell acute lymphoblastic leukemia.
Zhang Lenghe et al. Frontiers in oncology 2022 121057153
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Genomics improves risk stratification of adults with T-cell acute lymphoblastic leukemia patients enrolled in measurable residual disease-oriented trials.
González-Gil Celia et al. Haematologica 2022
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The genomic landscape of pediatric acute lymphoblastic leukemia
SW Brady et al, Nature Genetics, September 1, 2022
Realities of Pharmacogenomic and Minimizing Misconceptions and Medication Misadventures.
Duong Benjamin et al. Delaware journal of public health 2022 7(5) 12-15
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Integrated genomic analyses identify high-risk factors and actionable targets in T-cell acute lymphoblastic leukemia.
Zhu Haichuan et al. Blood science (Baltimore, Md.) 2022 4(1) 16-28
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SWOG 1318: A Phase II Trial of Blinatumomab Followed by POMP Maintenance in Older Patients With Newly Diagnosed Philadelphia Chromosome-Negative B-Cell Acute Lymphoblastic Leukemia.
Advani Anjali S et al. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2022 JCO2101766
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Genetic Ancestry and Childhood Acute Lymphoblastic Leukemia Subtypes and Outcomes in the Genomic Era.
Rabin Karen R et al. JAMA oncology 2022
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Association of Genetic Ancestry With the Molecular Subtypes and Prognosis of Childhood Acute Lymphoblastic Leukemia.
Lee Shawn H R et al. JAMA oncology 2022
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Prognostic value of low-level MRD in adult acute lymphoblastic leukemia detected by low- and high-throughput methods.
Kotrova Michaela et al. Blood advances 2022
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NUDT15 genetic testing-guided 6-mercaptopurine dosing in children with ALL likely to be cost-saving in China.
Wei XiaoXia et al. International journal of hematology 2021
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Association of Combined Focal 22q11.22 Deletion and IKZF1 Alterations With Outcomes in Childhood Acute Lymphoblastic Leukemia
DS Mangum et al, JAMA Oncology, August 19, 2021
[Second-generation Sequencing Analysis of Ph and Ph-like Childhood T-cell Acute Lymphoblastic Leukemia].
Liao Xin et al. Zhongguo shi yan xue ye xue za zhi 2021 29(4) 1101-1108
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Mutational profiling in acute lymphoblastic leukemia by RNA sequencing and chromosomal genomic array testing.
Yeung Cecilia et al. Cancer medicine 2021
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Next Generation Cytogenetics in Myeloid Hematological Neoplasms: Detection of CNVs and Translocations.
Chicano María et al. Cancers 2021 13(12)
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Implications of ACMG guidelines to identify high-risk acute lymphoblastic leukemia patients with hereditary cancer susceptibility syndromes (HCSS) in a highly consanguineous population.
Aslam Sara et al. BMC pediatrics 2021 21(1) 282
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An overview of genetic predisposition to familial hematological malignancies.
Hamadou Walid Sabri et al. Bulletin du cancer 2021
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Immune Reconstitution After Gene Therapy Approaches in Patients With X-Linked Severe Combined Immunodeficiency Disease.
Blanco Elena et al. Frontiers in immunology 2020 11608653
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Helpful Criteria When Implementing NGS Panels in Childhood Lymphoblastic Leukemia.
Vega-Garcia Nerea et al. Journal of personalized medicine 2020 Nov 10(4)
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[Diagnosis of adult Philadelphia chromosome-like acute lymphoblastic leukemia by fluorescence in situ hybridization].
Lin D N et al. Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 2020 Sep 41(9) 749-755
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The long road to the first FDA-approved gene therapy: chimeric antigen receptor T cells targeting CD19.
Braendstrup Peter et al. Cytotherapy 2020 22(2) 57-69
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Clinical utility of target capture-based panel sequencing in hematological malignancies: a multicenter feasibility study.
Yasuda Takahiko et al. Cancer science 2020 Jul
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Hereditary Predisposition to Hematopoietic Neoplasms: When Bloodline Matters for Blood Cancers.
Mangaonkar Abhishek A et al. Mayo Clinic proceedings 2020 Jun
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Genetic markers for treatment-related pancreatitis in a cohort of Hispanic children with acute lymphoblastic leukemia.
Grimes Allison C et al. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 2020 May
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Page last reviewed:
Feb 1, 2024
Page last updated:
May 16, 2024
Content source:
Public Health Genomics Branch in the Division of Blood Disorders and Public Health Genomics
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National Center on Birth Defects and Developmental Disabilities
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